Alfasigma Buys the Drug Jyseleca from Galapagos for €170 Million

Alfasigma expands its portfolio. The Italian group has purchased the drug Jyseleca from Galapagos for €170 million, in an operation that will close during the first quarter of 2024. The scientist’s treatment is aimed at patients with ulcerative colitis and rheumatoid arthritis (RA), according to the company statement.

Following the acquisition of the drug, Alfasigma intends to carry out a phase three clinical trial to develop a third indication for the therapy. Galapagos itself will also participate in this phase, investing forty million euros until June 2025 .

The Italian pharma will buy the entire business of Jyseleca, including marketing authorizations in Europe and the United Kingdom, commercial and medical affairs and drug development activities. Additionally, it will acquire approximately 400 Galapagos positions in fourteen European countries. In this sense, the seller will receive an initial payment of fifty million euros, possible milestone payments totaling €120 million and payments based on European sales.

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Jyseleca is aimed at patients with ulcerative colitis and rheumatoid arthritis

Filgotinib is marketed as Jyseleca in Europe and Japan for the treatment of adults with moderately to severely active RA who have responded inadequately or are intolerant to one or more disease-modifying antirheumatic drugs . Filgotinib is also used for the treatment of adult patients with moderately to severely active ulcerative colitis (UC) who have had an inadequate response, lost response, or were intolerant to conventional therapy or a biologic agent.

The Spanish subsidiary of Alfasigma is located in Tortosa, Barcelona, ​​and occupies an area of ​​1,600 square meters . 1,475 people work there and it has a portfolio of fifty references. The Spanish delegation of the company is the result of the merger in 2015 of Sigma-Tau and Alfa Wasserman and, previously, of the union of Geve Laboratories, in Tortosa, with Bama Laboratories, in 2003.

For its part, Galapagos is a global biotechnology company with operations in Europe and the United States dedicated to the development of transformative medicines to achieve longer and higher quality of life. The company combines science, technology and collaborative approaches to create a portfolio of therapies and biologics in oncology and immunology.

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First published in PlantaDoce. A third-party contributor translated and adapted the article from the original. In case of discrepancy, the original will prevail.

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