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Researchers at the Institute of Biomedicine of Seville identified molecular mechanisms explaining aggressive neuroblastoma. Dysregulation of Rho GTPase signaling, especially reduced Cdc42 activity driven by ARHGAP31,...
A Carlos III Health Institute team showed CRISPR-based gene therapy effectively targets Ewing sarcoma in preclinical models. Using a tumor-specific promoter, the treatment avoids harming healthy...