Valneva Wants to Make Sure its Covid-19 Vaccine is Safe for People Over 56
Valneva will soon be able to sell its Covid-19 vaccine candidate. On the European side, Valneva has broken off negotiations with the European Commission, preferring bilateral discussions on a country-by-country basis. The company still has to validate phase 3 and its complementary studies, which would allow the expected launch of the first French vaccine at the end of 2021 / the beginning of 2022.
After excellent results in phases 1 and 2, this news is not the best for Valneva’s anti-Covid-19 vaccine. The Saint-Herblain (Loire-Atlantique) based biotech has announced to launch an additional phase 3 trial for its vaccine candidate on August 12, 2021.
Although the laboratory does not specify the reasons for this new study, it indicates that its objective is to “generate safety and immunogenicity data” in people over 56. In short, a way to verify that the vaccine is safe for this age group. The trial will take place in New Zealand, with approximately 150 candidates. They will be vaccinated twice, 28 days apart.
Read more about Valneva and its vaccine candidate against Covid-19 and find the latest financial news with the Born2Invest mobile app.
Adapting to variants
A second cohort of 600 people “older than 12 years” will join the study for additional data. The goal: to compare data from “the vaccine candidate derived from a Covid-19 variant” to the original vaccine. The strain has yet to be confirmed, the laboratory said.
The results of this second cohort are very important for the biotech, as they would confirm that Valneva’s platform is adaptable to different variants if needed. “We are working on the variants of concern as part of our ongoing efforts to stay ahead of the virus,” said Juan Carlos Jaramillo, head of medical research, in a statement.
A competitive vaccine
If VLA2001 (the name of the vaccine) emerges victorious from these trials and Phase III, it has a strong chance of creating a strong competitive position alongside Pfizer-BioNTech and Moderna. Indeed, in addition to a vaccine platform that can be adapted to variants, this vaccine has the advantage of using another technology that has been validated and accepted for a long time: the inactivated and adjuvanted virus.
Its principle is simple. It consists in killing the virus before injecting it into the patient. The inactivated and therefore harmless virus will need adjuvants to trigger the immune reaction. Valneva’s adjuvant is produced by the American company Dynavax. The combination of the inactivated virus and the adjuvant allows the immune system to be trained. To date, Valneva is the only European player to develop a vaccine of this type.
This alternative technology would allow many countries to complete their “vaccine portfolio”. The United Kingdom has already signed an agreement with the group for the supply of 100 million doses if phase 3 is positive. On the European side, Valneva has broken off negotiations with the European Commission, preferring bilateral discussions on a country-by-country basis. The company still has to validate phase 3 and its complementary studies, which would allow the expected launch of the first French vaccine at the end of 2021 / the beginning of 2022.
(Featured image by Dimhou via Pixabay)
DISCLAIMER: This article was written by a third party contributor and does not reflect the opinion of Born2Invest, its management, staff or its associates. Please review our disclaimer for more information.
This article may include forward-looking statements. These forward-looking statements generally are identified by the words “believe,” “project,” “estimate,” “become,” “plan,” “will,” and similar expressions. These forward-looking statements involve known and unknown risks as well as uncertainties, including those discussed in the following cautionary statements and elsewhere in this article and on this site. Although the Company may believe that its expectations are based on reasonable assumptions, the actual results that the Company may achieve may differ materially from any forward-looking statements, which reflect the opinions of the management of the Company only as of the date hereof. Additionally, please make sure to read these important disclosures.
First published in L’USINENOUVELLE, a third-party contributor translated and adapted the article from the original. In case of discrepancy, the original will prevail.
Although we made reasonable efforts to provide accurate translations, some parts may be incorrect. Born2Invest assumes no responsibility for errors, omissions or ambiguities in the translations provided on this website. Any person or entity relying on translated content does so at their own risk. Born2Invest is not responsible for losses caused by such reliance on the accuracy or reliability of translated information. If you wish to report an error or inaccuracy in the translation, we encourage you to contact us.
Bitcoin Surges 4% after US Debt Limit Suspension Deal
While the tentative agreement has yet to be approved by Congress, its announcement has already had a positive impact. BTC...
Petro Government Asks Congress to Legalize Cannabis for Adult Use in Colombia
A project that seeks to legalize the cannabis market has never gone this far before, and those who support it...
How the Fintech Sector Helps with Financial Inclusion
The fintech industry can provide financial products and services that incentivize their use through internet and smartphone access. Fintech companies...
Peridot Solar Takes Over a 135 MW Agrivoltaic Project in Sicily from Iqony Solar Energy Solutions Italia
Peridot Solar, a company in FitzWalter Capital's portfolio, which invests in a wide range of sectors and asset classes, including...
Netpharmalab Reaches €3 Million in 2022 and Anticipates a 16% Increase in 2023
The company, which has 37 people on its staff, generates 80% of its turnover in the Spanish market and the remaining...
Business2 weeks ago
Creating an Online Jewelry Business: Step-by-Step Journey
Business5 days ago
The TopRanked.io Weekly Digest: What’s Hot in Affiliate Marketing [Week 21]
Business1 week ago
Gold and its Open Interest: Should You Invest in Gold?
Crowdfunding7 days ago
The FastucUP Campaign, Created to Encourage Sicilian Agribusiness Exports Started