ADmit Therapeutics Closes 4.2M Round to Launch its Alzheimer’s Test

ADmit Therapeutics continues to make progress against Alzheimer’s disease. The Spanish company, a spin-off of the Bellvitge Biomedical Research Institute (Idibell), has closed a €4.2 million financing round to launch its early diagnosis test against Alzheimer’s disease on the market in 2023, according to Marta Barrachina, CEO of ADmit Therapeutics.

The company was selected in 2020 by the European Commission under its EIC Accelerator funding programs to receive 3.3 million euros. The rest of the investment comes from Equality4Good, Ship2B’s social impact investment vehicle; Banc Sabadell’s BStartup; Wa4steam, an international association of women business angels; Genesis Biomed, a biomedical sector consultancy; Capital Cell, an equity crowdfunding platform specializing in biomedicine; and other investors. ADmit Therapeutics has also received public funding from EIT Health, the Center for the Development of Industrial Technology (Cdti) and the Ministry of Science and Innovation.

The main objective of ADmit Therapeutics is to develop and commercialize for clinical practice an early diagnostic test that will allow, through a blood test, to detect Alzheimer’s disease in those patients with the first memory complaints.

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ADmit Therapeutics expects to launch its test on the market next year

The test represents the determination of a series of proprietary biomarkers, not related to the protein that accumulates in the brain β-amyloid or tau. ADmit Therapeutics’ value proposition is based on an epigenetic analysis in blood, covering a large number of methylcytosines using next-generation sequencing techniques.

Given that mitochondrial dysfunction has been described at the systemic level prior to the appearance of β-amyloid ni tau brain aggregates, “the patented biomarkers may represent a very useful tool for early detection of Alzheimer’s patients in early stages of the disease and improve their quality of life,” Barrachina explained.

In the short term, the early detection test developed by ADmit Therapeutics will make it possible to optimize patient recruitment for clinical trials. People will be selected in an optimal way, which will increase the possibility of identifying a curative drug by demonstrating its efficacy and helping pharmaceutical companies to make progress in the fight against this type of dementia.

“In any disease, the earlier the problem is detected the better, but even more so in the case of Alzheimer’s, because you can be more than twenty years with the disease without having any symptoms,” explained the CEO of ADmit Therapeutics. “The most important problem is that, during this time, the neurons in the brain are dying and when the diagnosis arrives it is too late to repair the damaged tissues,” she remarked.

ADmit Therapeutics is a company that was born in 2017 and was created by Marta Barrachina, in addition to Ramón Reñe, doctor and former head of the Functional Unit of Dementias at Bellvitge University Hospital, and Jordi Gascón, neurologist specializing in dementias, section head of the Neurology Service and coordinator of the Functional Unit of Dementias at Bellvitge University Hospital.

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(Featured image by geralt via Pixabay)

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